Hydroxypropyl méthylcellulose (HPMC) Vente en gros

Hydroxypropyl Methylcellulose (HPMC) Uses

Hydroxypropyl Methylcellulose (HPMC) is mainly derived from refined cotton/wood pulp, which is alkalized to obtain cellulose, and then added with propylene oxide and methyl chloride for etherification to obtain cellulose ether.

HPMC Cellulose act as thickener, water retaining agent, dispersant, stabilizer, emulsifier, binder, excipient, film former in various industries. HPM cellulose is widely used in construction dry-mixed mortar, pharmaceutical, petrochemical, ceramics, paper, synthetic resin, leather, food and cosmetics and other industries.

KimaCell® Hydroxypropyl Methylcellulose (HPMC) has the advantages of wide application, small unit usage, good modification effect, and environmental friendliness. HPMC products can significantly improve and optimize product performance in the field of its addition, which is conducive to improving resource utilization efficiency and product added value. Environmentally friendly additives that are essential in various fields.

1. HPMC In Pharmaceutical

In the field of medicine, Hydroxypropyl Methylcellulose (HPMC) is an important pharmaceutical excipient, which can be used in drug sustained and controlled release preparations, vegetable capsules, tablet coatings, suspending agents, tablet binders, tablet disintegrants and other application scenarios.

2. Hydroxypropyl Methyl Cellulose In Food

Food grade Hydroxypropyl Methylcellulose (HPMC) is a recognized safe food additive. It can be used as a food thickener, stabilizer and moisturizer to thicken, retain water, and improve taste. It is widely used in developed countries, mainly for baked food, collagen Protein casings, whipped cream, fruit juices, sauces, meat and other protein products, fried foods, etc. China, the United States, the European Union, and many other countries allow HPMC to be used as a food additive.

The proportion of food-grade Hydroxypropyl Methylcellulose (HPMC) used in food production in China is relatively low. The domestic market is still in the stage of application and promotion, coupled with the high price of food-grade HPMC, HPMC is used in fewer fields in food production in my country. However, with the improvement of income, the scale of the food industry is expected to maintain steady growth in the long run. Moreover, with the improvement of people's awareness of healthy food, the penetration rate of HPMC as a health additive will gradually increase. The consumption of HPMC in the food industry expected to grow further.

3. HPMC For Construction

In Construction drymix mortar industry, Hydroxypropyl Methylcellulose is used as a water-retaining agent and retarder for cement mortar to make the mortar pumpable. HPMC Used as a binder in plaster, plaster, putty powder or other building materials to improve spreadability and prolong work time. HPMC can be used as paste tile, marble, plastic decoration, paste reinforcement, and can also reduce the amount of cement. The water-retaining performance of HPMC prevents the slurry from cracking due to drying too quickly after application, and enhances the strength after hardening.

Hydroxypropyl Methylcellulose Benefits

Hydroxypropyl methylcellulose (HPMC) offers a wide range of benefits across different industries. HPMC versatile nature as thickener, stabilizer, film-former, and water-retaining agent makes it an indispensable ingredient in pharmaceuticals, food products, cosmetics, and construction materials. Whether it's providing controlled drug release in pharmaceutical formulations, improving texture and stability in food products, enhancing the performance of cosmetic formulations, or optimizing the properties of construction materials, HPMC plays a vital role.HPMC offers numerous benefits due to its unique properties, making it a valuable ingredient in many products.

• Pharmaceutical Benefits:

a. Controlled Drug Release: HPMC is commonly used as a matrix former in oral solid dosage forms, such as tablets and capsules. It provides controlled drug release, ensuring a steady and sustained release of the active pharmaceutical ingredient (API) over an extended period. This feature is particularly beneficial for drugs that require a slow release pattern to maintain therapeutic efficacy.

b. Film Coating: HPMC forms a uniform and smooth film when applied to tablets or capsules, offering protection against environmental factors such as moisture, light, and air. It also improves the appearance, swallowability, and stability of the dosage form.

c. Mucoadhesive Properties: HPMC can adhere to the mucosal surfaces, enhancing the contact time and improving drug absorption. This property is useful in the development of various oral and ocular drug delivery systems.

• Food Benefits:

a. Thickening and Stabilization: HPMC acts as a thickening and stabilizing agent in food products. It imparts viscosity, texture, and creaminess to sauces, dressings, and dairy products. It prevents phase separation and maintains the homogeneity of food formulations.

b. Fat Replacement: HPMC can be used as a fat replacer in low-fat food products. It mimics the mouthfeel and texture of fats, providing a desirable sensory experience while reducing the calorie content.

c. Water Retention: HPMC has the ability to retain water, thereby preventing moisture loss and maintaining the juiciness and freshness of food products. It is particularly useful in baked goods, where it improves shelf life and texture.

• Cosmetics Benefits:

a. Thickening and Emulsifying Agent: HPMC cellulose is widely used in cosmetic formulations, such as creams, lotions, and shampoos, due to its excellent thickening and emulsifying properties. It improves the stability and consistency of cosmetic products, allowing for better spreadability and ease of application.

b. Film-Forming: When applied to the skin or hair, HPMC cellulose forms a protective film that helps to retain moisture, reducing water loss and maintaining hydration. It also enhances the longevity of cosmetic products on the skin or hair surface.

c. Suspending Agent: HPMC can suspend solid particles in cosmetic formulations, preventing their settling or sedimentation. This property is particularly useful in suspensions, scrubs, and exfoliating products.

• Construction Benefits:

a. Cement and Mortar Additive: HPMC acts as a thickener and water-retaining agent in cement-based products, such as mortars, tile adhesives, and renders. It improves workability, adhesion, and sag resistance, while reducing cracking and shrinkage.

b. Improved Open Time: Open time refers to the duration during which a construction material remains workable after application. HPMC extends the open time of adhesives, allowing for easier positioning and adjustment of tiles, wallpapers, and other materials.

c. Water Resistance: HPMC enhances the water resistance of construction materials, making them more durable and resistant to moisture-related damage. It improves the overall performance and lifespan of buildings and structures.

Overall, the hydroxypropyl methylcellulose benefits are vast and diverse. Its multifunctional properties make it an essential ingredient in a wide range of products, providing improved performance, stability, and user experience. As research and technology continue to advance, HPMC celluloseis likely to find even more applications in various industries, further demonstrating its value and versatility.

Le procédé de fabrication de l'hydroxypropylméthylcellulose (HPMC) implique plusieurs étapes pour modifier la cellulose, un polymère naturel dérivé de sources végétales. Le procédé comprend un traitement chimique et une réaction pour introduire des groupes hydroxypropyle et méthyle sur le squelette cellulosique. Explorons le processus de fabrication de HPMC en détail.

• Extraction de cellulose:

Le processus commence par l'extraction de la cellulose à partir de sources végétales. Les sources courantes comprennent la pâte de bois, le coton ou d'autres matières végétales fibreuses. La cellulose est généralement obtenue par une série de traitements mécaniques et chimiques, qui impliquent de décomposer la matière végétale et d'éliminer les impuretés pour obtenir un matériau cellulosique purifié.

• Traitement d'alcali:

Une fois la cellulose extraite, elle subit un traitement alcalin pour éliminer l'hémicellulose et les composants de la lignine. Ce traitement implique l'immersion de cellulose dans une solution alcaline, telle que l'hydroxyde de sodium (NaOH), pour décomposer les matériaux non cellulosiques. Le résultat est une cellulose purifiée avec un degré de pureté plus élevé.

• Etherification:

L'étape suivante est le processus d'éthérification, où des groupes hydroxypropyle et méthyle sont introduits sur le squelette cellulosique. Ceci est réalisé grâce à une série de réactions impliquant la cellulose et les réactifs appropriés.

A. Activation d'alcali: La cellulose purifiée est mise en suspension dans une solution alcaline, typiquement de l'hydroxyde de sodium, pour activer la cellulose et la rendre plus réactive.

B. Hydroxypropylation: La cellulose activée est ensuite traitée avec de l'oxyde de propylène (PO) ou un composé similaire. Le groupe hydroxypropyle du PO réagit avec les groupes hydroxyle de cellulose, conduisant à la fixation de groupes hydroxypropyle sur le squelette cellulosique.

C. Méthylation: Suite à l'étape d'hydroxypropylation, la cellulose avec des groupes hydroxypropyle attachés subit une méthylation. Cela implique la réaction de la cellulose hydroxypropylée avec du chlorure de méthyle ou un agent méthylant similaire. Le groupe méthyle de l'agent de méthylation réagit avec les groupes hydroxyle restants sur la cellulose, entraînant l'introduction de groupes méthyle sur le squelette cellulosique.

• Neutralisation et lavage:

Après le processus d'éthérification, le mélange réactionnel est neutralisé pour arrêter d'autres réactions et ajuster le pH. Des solutions acides ou basiques sont ajoutées pour neutraliser tout excès d'alcali ou d'acide présent dans le mélange. Le mélange neutralisé est ensuite lavé à fond pour éliminer tous les réactifs ou sous-produits résiduels, garantissant un produit HPMC purifié.

• Séchage et fraisage:

La dernière étape du processus de fabrication HPMC consiste à sécher et à fraiser le produit HPMC obtenu. Le produit est généralement séché en utilisant des méthodes de séchage à l'air chaud ou sous vide pour éliminer l'humidité et obtenir une poudre sèche. Le HPMC séché est ensuite broyé pour obtenir la taille et l'uniformité des particules souhaitées, ce qui donne une poudre fine prête à être emballée et distribuée.

Il convient de noter que le processus de fabrication spécifique de HPMC peut varier légèrement selon les fabricants et leurs méthodes exclusives. Cependant, les principes généraux et les étapes du processus restent cohérents.

En conclusion, le processus de fabrication de l'hydroxypropylméthylcellulose (HPMC) implique l'extraction de la cellulose à partir de sources végétales, suivie d'un traitement alcalin, d'une activation alcaline, d'une hydroxypropylation, d'une méthylation, d'une neutralisation, d'un lavage, d'un séchage, et fraisage. Ce processus aboutit à la production de HPMC, un composé polyvalent avec diverses applications dans des industries telles que les produits pharmaceutiques, l'alimentation, les cosmétiques et la construction.